Inny tytuł:

Immunoreaktywność dla endoteliny w hipokampie szczura po przemijającym całkowitym niedokrwieniu mózgu. II. Bariera krew-mózg

Wydawca:

Severus Publishing House

Miejsce wydania:

Warsaw

Typ obiektu:

Journal/Article

Abstrakt:

The effect of transient, global cerebral ischemia on the distribution of endothelin (ET) in blood-brain barrier (BBB) in CAI area of hippocampus long-time after ischemia was estimated using post-embedding immunogold technique. ET-like immunoreactivity as a gold particles was localized in all compartments of the blood-brain barrier e.g. in endothelial cells, in pericytes, in periendothelial space including basement membrane, and in astroglial processes. In control animal the density of labelling in all elements of BBB in CAI area of hippocampus was moderate. ET-like immunoreactivity (ET-like IR) was estimated 1 week - 12 months after ischemia. Intense ET-like IR in all elements of BBB was noted 2 and 6 months after ischemia. A potential pathophysiological role of endothelin in cerebral vasospasm in long-time after ischemia is well documented.

Czasopismo/Seria/cykl:

Folia Neuropathologica

Tom:

35

Zeszyt:

1

Strona pocz.:

49

Strona końc.:

59

Szczegółowy typ zasobu:

Article

Format:

pdf

Identyfikator zasobu:

oai:rcin.org.pl:71897

Język:

eng

Język streszczenia:

eng ; pol

Prawa:

Creative Commons Attribution BY 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitalizacja:

Mossakowski Medical Research Institute PAS

Lokalizacja oryginału:

Library of the Mossakowski Medical Research Institute PAS

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open