Publisher:

Państwowy Zakład Wydawnictw Lekarskich

Place of publishing:

Warszawa

Type of object:

Journal/Article

Abstract:

In glial cultures grown in vitro under various gas atmosphere, the activity of redox enzyme activities in glial cultures was studied.The activity of these enzymes is dependent on the oxygen content in the atmosphere, the solubility of oxygen in the medium, the age of the culture and the type of glial cells.The greatest decrease in enzymatic activity was observed in complete hyper- oxia and anoxia.Intermediate states of hypoxia and hyperoxia did not noticeably affect the activity of dehydrogenases.Young, 2—3-weel-old cultures, exhibited the greatest drop in enzymatic activities.The pattern of the enzymatic reactions and the distribution of activities in different types of glial cells were the same as in normal gas atmosphere.Succinic, NAD, glutamic, a-glycerophosphate, glucose-6-phosphate and lactic dehydrogenases showed the greatest decrease in activity.The enzymatic activity of all the dehydrogenases studied was directly dependent on the functional state and the morphology of the glial cells.

Relation:

Polish Medical Journal

Volume:

6

Issue:

6

Start page:

1582

End page:

1591

Detailed Resource Type:

Article

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:70617

Language:

eng

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open