Państwowy Zakład Wydawnictw Lekarskich
The morphologic pattern of pathological lesions in the central nervous system associated with uremia is discussed. Three illustrative cases are reported.The first case concerns a 70-year-old female patient in whom uremia was the outcome of a preterminal exacerbation of chronic glomerulonephritis. The morphologic changes in the brain, besides those characteristic of uremic encephalopathy, showed signs of allergic encephalitis typical of para-infectious and postvaccinational encephalitis.The second case concerns a 73-year-old male patient. Uremia was presumably connected with hydronephrosis caused by urinary retention due to prostatic adenomas. The changes in the brain in this case were few, with predominance of edema and moderate atherosclerotic lesions.In the third case, that of a 24-year-old male patient, uremia developed as a result of bilateral destruction of the kidneys by a tuberculous process. The morphological findings in the brain closely resembled those of typical uremic encephalopathy.In all three cases uremia was the result of renal disease, but the pathogenetic mechanism was different in each case. In the opinion of the authors, different pathogenetic mechanisms may be the reason for the different morphological changes in the central nervous system.
Creative Commons Attribution BY 4.0 license
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Mossakowski Medical Research Institute PAS
Library of the Mossakowski Medical Research Institute PAS
Feb 1, 2022
Apr 24, 2019
81
https://rcin.org.pl./publication/92177
Edition name | Date |
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Osetowska, Ewa, 1964, CHANGES IN THE CENTRAL NERVOUS SYSTEM INUREMIC CONDITIONS | Feb 1, 2022 |
Mossakowski, Mirosław Jan (1929–2001)
Mossakowski, Mirosław Jan (1929–2001)
Mossakowski, Mirosław Jan (1929–2001)
Mossakowski, Mirosław Jan (1929–2001)
Mossakowski, Mirosław Jan (1929–2001)
Mossakowski, Mirosław Jan (1929–2001)