Subtitle:

EFFECT OF EXPERIMENTAL HYPOGLYCEMIA ON THE GLYCOGEN CONTENT AND THE ACTIVITY OF GLYCOGEN-METABOLIZING ENZYMES IN THE RAT BRAIN

Publisher:

Zakład im. Ossolińskich - Wydawnictwo Polskiej Akademii Nauk

Place of publishing:

Wrocław ; Warszawa ; Kraków

Abstract:

The study deals with the changes in the glycogen content and the glycogenphosphorylase activities in the rat brain following single subcutaneous administrationof insulin in a lu/100 g body weight dose. The treatment caused a decreaseof blood glucose level persisting for 6 hrs, with a maximum drop (to ca. 35% ofthe control level) observed 2-3 hrs after the hormone administration. The hypoglycemicperiod was accompanied by a decrease of the brain glycogen content coinciding with a rise in the activity of the active, 5’-AMP-independent form ofglycogen phosphorylase.

Relation:

Neuropatologia Polska

Volume:

17

Issue:

4

Start page:

523

End page:

533

Detailed Resource Type:

Article

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:69149

Language:

pol

Language of abstract:

eng ; rus

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open