Subtitle:

Effect of indomethacin on ischemic brain damage in Mongolian gerbils (Meriones unguiculatus)

Publisher:

Zakład im. Ossolińskich - Wydawnictwo Polskiej Akademii Nauk

Place of publishing:

Wrocław ; Warszawa ; Kraków

Type of object:

Journal/Article

Abstract:

The study aimed in establishing the effect of indomethacin, a well known inhibitor of cyclooxygenase, on the dynamics and nature of postischemic brainlesions in Mongolian gerbils in which cerebral ischemia was due to bilateral ligation of the common carotid arteries for a period of 30 min. In experimentalanimals carotid ligation was preceded by intraperitoneal injection of indomethacin,dissolved in Krebs-Ringer solution in a dose of 10 mg'l kg of bodyweight. Control animals were not pretreated with indomethacin. The brains of both group of animals were examined during 6 h of postischemic period in 1 hintervals.

Relation:

Neuropatologia Polska

Volume:

21

Issue:

3

Start page:

287

End page:

301

Detailed Resource Type:

Article

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:69024

Language:

pol

Language of abstract:

eng ; rus

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open