Praca doktorska została wykonana w Zakładzie Chemii i Biologii Strukturalnej Kwasów Nukleinowych
DNA exists as a double helical structure, called B helix, which is the most commonstructure. In native RNA, double-stranded helical regions are short (on average 5–7 basepairs long) and RNA contains many different structural motifs, such as: hairpins,symmetrical and asymmetrical single or double nucleotide bulges, internal loops. Thepolymorphic nature of nucleic acids allows to adopt a variety of structures depending onthe sequences, the local environment, the presence of molecules or chemicalmodifications. For examples, DNA and RNA can form parallel-stranded duplexes, triplehelical structures (triplexes) or four-stranded structures (quadruplexes).
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
Sep 8, 2021
Sep 8, 2021
259
https://rcin.org.pl./publication/245572
Edition name | Date |
---|---|
Badania termodynamiczne, strukturalne i biologiczne niekanonicznych form DNA i RNA | Sep 8, 2021 |
Tworak, Aleksander
Ruszkowski, Miłosz
Lewandowski, Dominik
Koralewska, Natalia