Institutional creator:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases

Contributor:

Walczak, Ewa ; Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases

Place of publishing:

Warsaw

Description:

Electron microscopy analysis of the heart biopsy

Abstract:

Electronmicroscopy evaluation revealed focal changes in the course of myofilaments and their disorganization. In some cardiomyocytes ultrastructurally disorganized sarcomeres and scattered myofilaments were present in the vicinity of altered cell nuclei. Often in such an area of myofilament lysis an aggregation of mitochondria characterized by a light electron matrix was observed. Most of cardiomiocytes nuclei were characterized by discontinuity of the nuclear membrane and bright chromatin. Insarcoplasm, and in the vicinity of ultrastructurally altered nuclei numerous autophagal structures were seen. In the extracellular space capillary vesselsforming loops were observed. Vascular endothelial cells were characterized by a bright cytoplasm.

Detailed Resource Type:

Files ; Photography

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:156886

Language:

pol ; eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open