Institutional creator:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases

Contributor:

Walczak, Ewa ; Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases

Place of publishing:

Warsaw

Description:

Electron microscopy analysis of the heart biopsy

Abstract:

Mitral and tricuspid valve regurgitation.Ceroidolipofuscinosis.Ultrastructural analysis revealed the presence of abundant osmophilic granular material deposits in cardiomyocytes.This material was surrounded by a membrane.Within these deposits lipid vacuoles were observed.Characteristic granular deposits were also present in the vicinity or inside the mitochondria.Numerous myelin-like bodies were visible in the karyoplasm.Cardiomyocyte nuclei in the examined material were characterized by an irregular shape and numerous invaginations in the nuclear envelopes. Ruptures of the nuclear envelopes were often observed.

Detailed Resource Type:

Files ; Photography

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:154700

Language:

pol ; eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open