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Wielokrotne klonowanie zarodków zwierząt gospodarskich
Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
The main purpose of nuclear transfer in domestic species is to produce a large number ofidentical animals. There are two main ways to produce clones by nuclear transfer. One is touse the ICM and ED cells cultured under special conditions, as donor nuclei. The other way isto use the nuclear transfer embiyo itself as the donor for the next generation of cloning (multiplegenerational cloning). The in vitro and in vivo developmental ability of nuclear transferred embryosis the same in the case of the first three generations. A limited number of multiple-generationclones were transferred into recipient heifers, resulting in offspring from 1, 11 and 111 generationclones. The strategy to increase the efficiency of multiple generational bovine embryo cloning isdiscussed as well as the possible use of rabbit embryos as an experimental model.
Biotechnologia, vol.41, 2 (1998)-.
0860-7796 ; oai:rcin.org.pl:144334 ; IChB B-37
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
Nov 18, 2020
Oct 26, 2020
522
https://rcin.org.pl./publication/179648
Edition name | Date |
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Wielokrotne klonowanie zarodków zwierząt gospodarskich | Nov 18, 2020 |
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan
Modliński, Jacek A. Karasiewicz, Jolanta
Karasiewicz, Jolanta Modliński, Jacek A.