Subtitle:

Complexity of Class 11 Genes - the Regulation of Transcription

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstract:

The control of eucaryotic class II genes transcription is unusually complicated because it is the first stage of their expression in the cell. The assortmentof specific gene coding sequence as a process of selection of submission for expression genes particularly essential is. In this process, beside RNA polymeraseII, the basic transcription initiation factors that form different initiation complexes with enzyme and DNA take part, as well as other protein factors, oftentissue specific that interact with fragment of DNA located in the distant place ofthe start of transcription. The formation of transcription complex, its components and possible interaction are discussed. The control ofthis process are discussed on the example of contribution of protein kinases and phosphatasesmodifying individual proteins, influencing the change of their mutual interactions and, in consequence, differentiating transcription level ofspecific genes.

Relation:

Biotechnologia, vol.58, 3 (2002)-.

Volume:

58

Issue:

3

Start page:

107

End page:

123

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796 ; oai:rcin.org.pl:137880 ; IChB B-54

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open