Subtitle:

Pharmaceutical biotechnology: The achievements of 20th century and the expectations in 21th century

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstract:

Pharmaceutical biotechnology is 60 years old. Its development one can divide into three essential periods. Two of them have proceeded in past century.The first period started during the Second World War with the industrial production of penicillin and was microbiology-based (microbial metabolites as drugs).The second one was genetic engineering-based and started in 1982, when human insulin synthesized in recombinant bacteria was introduced by pharmaceutical industry to health care. The third period began in 2001 with the first descriptions of the human genome, and is genome-based (also proteome-based).Molecular biology with its new areas - genomics, farmacogenomics and proteomics, together with bioinformatics and other sophfisticated tools developedat the end of XX century and introduced (to the pharmaceutical and medicalbiotechnology of the XXI century) very new ideas and new approaches to drugdiscovery and designin. Pharmaceutical biotechnology (as well as pharmaceutical industry as a whole and world biotechnology as a whole) is entering uponthe third phase of its development, a very integrated and globalized one.

Relation:

Biotechnologia, vol.59, 4 (2002)-.

Volume:

59

Issue:

4

Start page:

56

End page:

78

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796 ; oai:rcin.org.pl:137494 ; IChB B-55

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open