Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular
Muscle segment examination in light & electon microscopy
A 40-year-old patient with congenital myopathy was examined. A biceps sinister biopsy wasperformed.Electronmicroscopy analysis revealed presence of normal diameter muscle fibers. They werecharacterized by preserved myofibrils and sub-membranous located cell nuclei but damage to nuclearenvelope and ultrastructural abnormalities within nuclei were observed. In some fibres focal ruptureof contractile apparatus was observed.Also fibers of small diameter characterized by decay of contractile apparatus were seen.The accumulation of a large amount of autophagal structures was observed. In some fibres almostthe entire muscle fiber was filled by autophagal structures.
Creative Commons Attribution BY 4.0 license
Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -
Mossakowski Medical Research Institute PAS
Library of the Mossakowski Medical Research Institute PAS
Feb 1, 2022
Jul 13, 2020
27
https://rcin.org.pl./publication/165786
Edition name | Date |
---|---|
opis nr 42/07 | Feb 1, 2022 |
Fidziańska-Dolot, Anna (1930–2015)
Fidziańska-Dolot, Anna (1930–2015)