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Mazurek, Urszula ; Janikowska, Grażyna ; Wydmuch, Zenobia ; Wilczok, Tadeusz
Viral infections in xenotransplantation and their detection strategies
Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN
Utilizing animals as organ donors for humans may cause transmission of foreign species pathogens to the recipient. To minimize the risk of transmission of infectious diseases from animals to humans, the strategy of appropriate animal selection is being assessed. The aim of the selection of specific pathogen-free pigs was the differentiation of active viruses from latent ones in both the recipients and donors in search of the host gene expression profiles which would differentiate the beginning of transplant rejection from an active infection. Additionally, the researchers searched for gene profile expressions indicating the type of infection which would considerably reduce the time of detection, and the cause of disease in the recipient which would offer a better chance of a positive result of the surgery.
Biotechnologia, vol.72, 1 (2006)-.
0860-7796 ; oai:rcin.org.pl:87812 ; IChB B-68
Biblioteka Instytutu Chemii Bioorganicznej PAN
Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0
Instytut Chemii Bioorganiczneji Polskiej Akademii Nauk
Instytut Chemii Bioorganiczneji Polskiej Akademii Nauk
Oct 2, 2020
Dec 13, 2019
252
https://rcin.org.pl./publication/114774
Edition name | Date |
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Infekcje wirusowe w ksenotransplantacjach i strategie ich wykrywania | Oct 2, 2020 |
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan
Nowak, Jacek K.