Function of the liver and some biochemical indices during 3-hour extracorporeal perfusion in a patient with acute liver failure

Rosnowska, Maria; Olszewski, Waldemar; Pomaski, Ireneusz; i in.

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Function of the liver and some biochemical indices during 3-hour extracorporeal perfusion in a patient with acute liver failure

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Title: Function of the liver and some biochemical indices during 3-hour extracorporeal perfusion in a patient with acute liver failure

Abstract:

Some biochemical indices established during extra-corporeal perfusion ofpig liver with blood of the patient with acute liver failure were described. Theliver failure was a complication of viral hepatitis. There were abnormalitiesduring perfusion in acid-base equilibrium manifested by noncompensatedrespiratory alkalosis with hypopotassemia.The serum bilirubin level decreased while pyruvate and lactate concentrationsincreased. The serum alanine-aminotransferase activity was lower than in normals.The serum aspartate aminotransferase activity was higher and it appeared thatthis increase was caused by mitochondrial fraction. This suggestion was confirmedby the observation that in this condition the glutamate dehydrogenase activity(typical mitochondrial enzyme) was also elevated. During perfusion the increaseof glucose uptake by the patient was observed. The serum glucose concentrationshould be then continuously controlled.

Relation:

Polish Medical Journal

Volume:

Issue:

Start page:

360

End page:

367

Detailed Resource Type:

Artykuł

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:81342

Language:

eng

Rights:

Licencja Creative Commons Uznanie autorstwa 4.0

Terms of use:

Zasób chroniony prawem autorskim. [CC BY 4.0 Międzynarodowe] Korzystanie dozwolone zgodnie z licencją Creative Commons Uznanie autorstwa 4.0, której pełne postanowienia dostępne są pod adresem: ; -

Digitizing institution:

Instytut Medycyny Doświadczalnej i Klinicznej im. M. Mossakowskiego Polskiej Akademii Nauk

Original in:

Biblioteka Instytutu Medycyny Doświadczalnej i Klinicznej im. M. Mossakowskiego PAN

Projects co-financed by:

Program Operacyjny Polska Cyfrowa, lata 2014-2020, Działanie 2.3 : Cyfrowa dostępność i użyteczność sektora publicznego; środki z Europejskiego Funduszu Rozwoju Regionalnego oraz współfinansowania krajowego z budżetu państwa

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Last modified:

Feb 1, 2022

In our library since:

Sep 26, 2019

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All available object's versions:

https://rcin.org.pl./publication/106300

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Edition name	Date
Rosnowska, Maria, 1972, Function of the liver and some biochemical indices during 3-hour extracorporeal perfusion in a patient with acute liver failure	Feb 1, 2022