Publisher:

PZWL

Place of publishing:

Warszawa

Type of object:

Journal/Article

Abstract:

Experimental constriction of the common bile duct up to 1—99°/o of its lumen width, was performed by the authors. Experiments were carried out on 35 dogs. Marked cholestasis and dilation of extra- and intrahepatic biliary tracts followed the induced constriction. The changes developed after lapse of some 8—10 days. Microscopical specimens showed the images of cholestasis and fine-celled infiltrations within periportal spaces, at which these changes were visible since the 10th day. In the later period, after lapse of 50—60 days hyperplasia of connective tissue and of biliary tubules appeared. This process reached its maximum between 130th and 150th day of the experiment. In one case typical biliary liver cirrhosis was found after lapse of 156 days. Marked increase of the blood serum bilirubinę, basic phosphatase and pyruvic transaminase level followed already in the first week after constriction. Intensification of biochemical and anatomopathological changes did not depend upon the degree of constriction of the common bile duct and was the same as well at l°/o as w’ell at 99°/o of the lumen constriction. Only the survival time of animals was the longer the minor was the constriction.

Relation:

Polski Przegląd Chirurgiczny

Volume:

36

Issue:

6

Start page:

767

End page:

776

Detailed Resource Type:

Article

Resource Identifier:

oai:rcin.org.pl:80936

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Copyright holder:

Olszewski, Waldemar

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Institute of Literary Research PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open