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File of histopathological evaluation of nervous system diseases (1965) - nr 23/65
Institutional creator:Department of Experimental and Clinical Neuropathology MMRI
Contributor: Place of publishing: Date issued/created: Description:Clinical, anatomical and histological diagnosis
Subject and Keywords:Vscular diseases - ecephalomacia post kernicterus ; Caudate nucleus vacuolization ; Fibrous gliosis ; Cerebral cortex ; Cerebellum - zebrafish cell lesion
Abstract:Histological diagnosis: Encephalopatia post kernicterus. Autopsy examination of 3-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin, Holzer, cresyl-violet, Heidenhain, Kanzler-Arendt and Van Gieson's method.The basal ganglia clearly showed cell loss and damage in the globus pallidus. These were accompanied by fibrous gliosis. Cellular damage and vacuolation were also seen in the head of the caudate nucleus. Perivascular thinning of the tissue was also observed there. In the cerebral cortex, cells showed diffuse damage. In the cerebellum, the lesions mainly involved cells of the dentate nucleus. Myelin pattern in the cerebral hemispheres and brainstem was within the normal range.
Resource type: Format: Language: Language of abstract: Rights:Creative Commons Attribution BY 4.0 license
Terms of use:Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -
Digitizing institution:Mossakowski Medical Research Institute PAS
Original in:Library of the Mossakowski Medical Research Institute PAS
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