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New strategies for application of plasmid and viral vectors in gene therapy
Subtitle:New strategies for application of plasmid and viral vectors in gene therapy
Creator:Józkowicz, Alicja ; Dulak, Józef
Publisher:Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
Date issued/created: Subject and Keywords: Abstract:The success of gene therapy depends on development of efficient and safe delivery vectors. Recently, significant progress has been achieved in application of various non-viral delivery methods and numerous modified viral vectors for experimental gene therapy. Some of those vectors have been also successfully used in clinical trials of gene therapy. Further progress in this still promising, although not-fulfilling all expectations, treatment is dependent on the careful evaluation of the modes of transgene delivery and regulation of transgene expression in the diseased tissues. In this review the current progress in development of some of the tools for therapeutic gene transfer is discussed.
Relation:Biotechnologia, vol.78, 3 (2007)-.
Volume: Issue: Start page: End page: Resource type: Detailed Resource Type: Format: Resource Identifier: Source:Library of Institute of Bioorganic Chemistry PAS
Language: Language of abstract: Temporal coverage: Rights:Creative Commons Attribution BY-SA 4.0 license
Terms of use: Digitizing institution:Institute of Bioorganic Chemistry of the Polish Academy of Science
Original in:Institute of Bioorganic Chemistry of the Polish Academy of Science
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