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File of histopathological evaluation of nervous system diseases (1966) - nr 162/66
Institutional creator:Department of Experimental and Clinical Neuropathology MMRI
Contributor: Date issued/created: Description:Clinical, anatomical and histological diagnosis
Subject and Keywords:Developmental deffects ; Hydrocephalus
Abstract:Histological diagnosis: Hydrecephalus et laesirnes parenchymatosae secundarie in cerebrum cum Arnold-Chiarie syndroma. Autopsy examination of 9-month-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections by Heidenhain, Van Gieson's and Cresyl violet stain.Cross sections through the cerebral hemispheres revealed a huge hydrocephalus. The cerebral cortex was very severely artifactually damaged, however, cellular de-fects and huge congestion were undoubted. Similar findings were observed in the white matter. In the cerebellum, gliosis and vascular stasis, also present in the brainstem were noticed. In addition, at the level of the midbrain and the medulla ob-longata, nerve cell damage and an overall pale myelin pattern were observed. The meninges, especially at the level of the brainstem and cerebellum, showed features of fibrosis inadequate to the age of the child and related to the disease process.
Resource type: Format: Language: Language of abstract: Rights:Creative Commons Attribution BY 4.0 license
Terms of use:Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -
Digitizing institution:Mossakowski Medical Research Institute PAS
Original in:Library of the Mossakowski Medical Research Institute PAS
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