Title:

Studies of heart ultrastructure in various diseass by prof A. Fidziańska-Dolot: familial cardiomyopathy - 22/07

Creator:

Fidziańska-Dolot, Anna (1930–2015)

Institutional creator:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases

Contributor:

Walczak, Ewa

Place of publishing:

Warsaw

Date issued/created:

2007

Description:

Electron microscopy analysis of the heart biopsy

Subject and Keywords:

Familial cardiomyopathy ; Autophagy

Abstract:

Ultrastructural analysis revealed focally unchanged cardiomyocytes architecture.However, disorganization of sarcomeres and atrophy of myofibrils was observed in some cells, especially in the vicinity of cardiomyocytes nuclei . Many mitochondria were swollen and characterized by a bright mitochondrial matrix and loss of cristae.Vacuole-like structures and lipofuscin deposits were abundant.Focally, large accumulation of glycogen granules and autophagy were observed.

Resource type:

Text ; Image

Detailed Resource Type:

Files ; Photography

Format:

pdf

Language:

pol ; eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open