Title:

Studies of heart ultrastructure in various diseases by prof A. Fidziańska-Dolot: heart failure - 9/08

Creator:

Fidziańska-Dolot, Anna (1930–2015)

Institutional creator:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases

Contributor:

Walczak, Ewa ; Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases

Place of publishing:

Warsaw

Date issued/created:

2008

Description:

Electron microscopy analysis of the heart biopsy

Subject and Keywords:

Heart failure

Abstract:

Ultrastructural analysis revealed abnormalities in the morphological structure of thecardiomyocytes. In many cardiomyocytes changes in the structure of the sarcomeres wereobserved. The course of myofibrils was irregular. The cytoplasm of cardiomyocytes was filledwith numerous mitochondria and vacuolar structures. Except mitochondria, numerousfat droplets were present in the cytoplasm of cardiomyocytes. In most cells,frequently clusters of membrane-surrounded glycogen granules were seen.Within glycogen clusters, autophagous vacuoles were often observed.Cardiomyocytes nuclei were irregularly shaped.

Resource type:

Text ; Image

Detailed Resource Type:

Files ; Photography

Format:

pdf

Language:

pol ; eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open