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Biotechnology of drugs on the verge of 21st century
Subtitle:Biotechnology of drugs on the verge of 21st century
Creator: Publisher:Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
Date issued/created: Subject and Keywords: Abstract:At present the most classical pharmaceutical technologies have reached ahigh level of industrial perfection. The best example of those achievements isthe biotechnology of penicillins. Biosynthetic penicillin production using highlyproductive strains ofPenicillium chrysogeniim is followed by enzymatic hydrolysisof the product using microbial penicillin acylase, the best sources of which arerecombinant strains of Escherichia coli. The resulting 6-aminopenicillanic acid isthe starting material for chemical synthesis of a large number of semisyntheticpenicillins. Research and development of the biotechnology of antibiotics gavesolid foundations to other biotechnological processes in the pharmaceutical industry, i.e. production of amino acids, organic acids, enzymes and enzyme inhibitors, vitamins, alkaloids, dextran, steroid drugs and others.
Relation:Biotechnologia, vol.50, 3 (2000)-.
Volume: Issue: Start page: End page: Resource type: Detailed Resource Type: Format: Resource Identifier: Source:Library of Institute of Bioorganic Chemistry PAS
Language: Language of abstract: Temporal coverage: Rights:Creative Commons Attribution BY-SA 4.0 license
Terms of use: Digitizing institution:Institute of Bioorganic Chemistry of the Polish Academy of Science
Original in:Institute of Bioorganic Chemistry of the Polish Academy of Science
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