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Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
Date issued/created: Subject and Keywords: Abstract:Many yeasts secrete proteins which are toxic for pathogenic and non-pathogenic microorganisms. These toxins, mostly glycoproteins, consist of membrane-binding subunits which interact with carbohydrates (e.g. 1,6-|3-D-glucanor a-mannan) on the cell wall ofsensitive strains. The killing effect is presentedby membrane permeation, cell lysis or inhibition of the cell cycle.It is also suggested that these killer glycoproteins, similar in structure tolectins, can mediate self-adhesion ofthe pathogenic microorganisms, thus stimulating their excretion from the intestines of infected mammals. It is supposedthat the above interactions could be important for therapeutic applications, especially for enteric diseases.
Relation:Biotechnologia, vol.55, 4 (2001)-.
Volume: Issue: Start page: End page: Resource type: Detailed Resource Type: Format: Resource Identifier: Source:Library of Institute of Bioorganic Chemistry PAS
Language: Language of abstract: Temporal coverage: Rights:Creative Commons Attribution BY-SA 4.0 license
Terms of use: Digitizing institution:Institute of Bioorganic Chemistry of the Polish Academy of Science
Original in:Institute of Bioorganic Chemistry of the Polish Academy of Science
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