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BSE - możliwości identyfikacji i profilaktyki
Subtitle:BSE - Identification and prophylactics
Creator:Słota, Ewa ; Natonek, Małgorzata ; Żyga, Agata ; Rejduch, Barbara
Publisher:Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN
Date issued/created: Subject and Keywords: Abstract:Prion diseases (for example: scrape of sheep, BSE, CJD of humans) areamong the most notable central nervous system degenerative disorders causedby the accumulation of modified cellular protein. The conversion of PrP(C) (thenormal cellular protein) into PrP(Sc) (the abnormal disease-causing isoform) involves a conformation change whereby the a-helical content diminishes and theamount of P sheet increases. PrP (Sc) is partially resistant to proteases, temperature, high and low pH. Because the incidence of prion diseases is due to severalfactors, various efforts need to be taken to reduce the scale and consequencesof the disease. They include post-mortem and in vivo diagnosis and prophylactics, i.e. monitoring of animals and feed control.
Relation:Biotechnologia, vol.56, 1 (2002)-.
Volume: Issue: Start page: End page: Resource type: Detailed Resource Type: Format: Resource Identifier: Source:Biblioteka Instytutu Chemii Bioorganicznej PAN
Language: Language of abstract: Temporal coverage: Rights:Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0
Terms of use: Digitizing institution:Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
Original in:Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
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