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Kurzyńska-Kokorniak, Anna ; Jaskólski, Mariusz ; Figlerowicz, Marek
Publisher:Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN
Date issued/created: Subject and Keywords: Abstract:Human immunodeficiency virus (HIV), the causative agent ofAIDS, belongsto the particularly dangerous and, as a result, the most extensively studied viruses. Until now no effective method protecting against this pathogen has beendeveloped. The major problem is the unusual genetic variability of HIV, whichhelps the virus to escape from immunological response and to produce drug-resistant mutants. Most of the collected data suggest that HIV-encoded reverseiransciiptase (HIV RT) is the main facto.- responsible for the continuos generation of new viral variants. There are two primary mechanisms involved in thegeneration of HIV mutants: high error prone replication and genetic RNA recombination. In this article both processes are discussed in detail.
Relation:Biotechnologia, vol.56, 1 (2002)-.
Volume: Issue: Start page: End page: Resource type: Detailed Resource Type: Format: Resource Identifier: Source:Biblioteka Instytutu Chemii Bioorganicznej PAN
Language: Language of abstract: Temporal coverage: Rights:Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0
Terms of use: Digitizing institution:Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
Original in:Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
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