Title:

Files for neuromuscular diseases (CZD) - nr 15182

Creator:

Fidziańska-Dolot, Anna (1930–2015)

Contributor:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular

Place of publishing:

Warsaw

Description:

Muscle segment examination in electron microscopy

Subject and Keywords:

Cell nucleus - structure ; Muscle cells ; Nucleopathy

Abstract:

Electronmicroscopy analysis of the biopsy revealed some fibers of the correct diameter, preserved myofibrilsstructure and normal, located under the sarcolemma nuclei.In addition to fibers of normal diameter and preserved sarcomere structure, muscle fibers of myotube-likemorphology, characterized by small diameter and centrally located nucleus, or row of nuclei(depending on the cross-section) were observed.In both types of fibers, an abnormal structure of cell nuclei, characterized by folding of the nuclearenvelope and excessive concentration of chromatin was observed.Microscopic image of the biopsy suggests congenital fiber-type disproportion (CFTS) andabnormalities in nuclei may suggest nucleopathy.

Resource type:

Text ; Image

Detailed Resource Type:

Photography ; Files

Format:

pdf

Language:

pol

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open