Title:

Files for neuromuscular diseases (2011) - nr 27/11

Creator:

Fidziańska-Dolot, Anna (1930–2015)

Contributor:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular

Place of publishing:

Warsaw

Date issued/created:

2011

Description:

Muscle segment examination in light & electon microscopy

Subject and Keywords:

Metabolic defect

Abstract:

A 28-year-old patient with suspected metabolic defect was examined. A biopsy of quadriceps sinis-ter was performed. Electron microscopy revealed preserved architecture of muscle fibers, but in type I muscle fibres damaged mitochondria characterized by light mitochondrial matrix and partially or totally devoid of mitochondrial cristae were seen. Also quite numerous fat droplets were observed.A defect of mitochondrial enzymes was suspected. Biochemical examination of carnitine palmitoyltransferase in the muscle tissue was performed and the result was 0,57 nM/mgB/min (Norm 6,5-18 nM/mgB/min).

Resource type:

Text ; Image

Detailed Resource Type:

Photography ; Files

Format:

pdf

Language:

pol

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open