Title:

The structure, medicinal properties and biosynthesis of cyathane diterpenoids ; Biotechnologia

Subtitle:

The structure, medicinal properties and biosynthesis of cyathane diterpenoids ; Journal of Biotechnology, Computational Biology and Bionanotechnology

Creator:

Krzyczkowski, Wojciech ; Malinowska, Eliza ; Herold, Franciszek

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Date issued/created:

2008

Subject and Keywords:

biotechnology

Abstract:

This paper describes an unusual type of diterpenoids, called cyathins, and presents their structure, biosynthesis and biological activities. These secondary metabolites have been isolated during the last 35 years from mycelia, culture broths and fruiting bodies of several species of mushrooms such as Cyathus helenae, C. striatus, Hericium erinaceum and Sarcodon scabrosus. Cyathane diterpenoids are known to have a potent stimulating effect on Nerve Growth Factor synthesis and can became potential therapeutic agents for the treatment of neurodegenerative disorders, for instance Alzheimer’s disease. Cyathins also possess anti-imflammatory and antimicrobial activity.

Relation:

Biotechnologia, vol.80, 1 (2008)-.

Volume:

80

Issue:

1

Start page:

146

End page:

167

Resource type:

Text

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open