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Ewolucja chromosomów eukariotycznych - od baz danych do modeli komputerowych i z powrotem
Subtitle:Journal of Biotechnology, Computational Biology and Bionanotechnology
Creator:Mackiewicz, Dorota ; Waga, Wojciech ; Cebrat, Stanisław
Publisher:Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN
Date issued/created: Description: Subject and Keywords: Abstract:Computer simulations of chromosomes’ and genomes’ evolution suggest that the genes located on relatively large and densely packed chromosomes should be grouped in clusters. Clusters located on homologous chromosomes may complement their defects or they may co-operate providing selective advantage to their hosts. Since recombination inside clusters is harmful, selection leads to the uneven distribution of recombination events along chromosomes - relatively high recombination in the subtelomeric regions and low recombination in the central regions of chromosomes. Uneven distribution of recombinations enables sympatric speciation which can not be predicted by the mean field theories of evolution. Further studies of chromosome evolution require more precise data (the best - full sequences) of many closely related genomes belonging to the same species.
Relation:Biotechnologia, vol.91, 4 (2010)-.
Volume: Issue: Start page: End page: Resource type: Detailed Resource Type: Format:application/pdf ; application/pdf
Resource Identifier: Source:Biblioteka Instytutu Chemii Bioorganicznej PAN
Language: Language of abstract: Temporal coverage: Rights:Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0
Terms of use: Digitizing institution:Instytut Chemii Bioorganiczneji Polskiej Akademii Nauk
Original in:Instytut Chemii Bioorganiczneji Polskiej Akademii Nauk
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