Title:

File of histopathological evaluation of nervous system diseases (1962) - nr 230/62

Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

K.Renkawek, dr med.

Place of publishing:

Warsaw

Date issued/created:

1962

Description:

Clinical, anatomical and histological diagnosis

Subject and Keywords:

Autopsy examination of 79-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin and van Gieson method.A specimen taken from the temporal lobe showed extensive pale necrosis involving both the cortex and the white matter. Numerous macrophages, juvenile vessels, and fibroblasts were present in the dissolving tissue. The tissue around the necrotic focus showed stimulated forms of astrocytic glial and microglia. There was a band-like necrotic focus with single macrophages, glial and fibroblasts in the inner capsule. Stimulated forms of astroglia were found around the focus. The meningeal and cerebral vessels showed features of vitrification and fibrosis. The perivascular spaces were dilated, the tissue around the vessels had a diffuse structure. In the cerebral cortex, some cells were shrunken with dark nuclei resembling ischemic disorder.Histological diagnosis: Encephalomalacia cerebri.

Abstract:

W skrawku pobranym z płata skroniowego widoczna była rozległa martwica blada obejmująca zarówno korę jak i substancję białą. W rozpływającej się tkance występowały liczne makrofagi, młode naczynia i fibroblasty. W tkance wokół ogniska martwicy stwierdzono pobudzone formy gleju astrocytarnego i mikrogleju. W torebce wewnętrznej było pasmowate ognisko martwicy z pojedynczymi makrofagami, glejem i fibroblastami. Wokół ogniska stwierdzono pobudzone formy astrogleju. Naczynia opon i mózgu wykazywały cechy szkliwienia i włóknienia. Przestrzenie okołonaczyniowe były poszerzone, tkanka wokół naczyń miała strukturę rozrzedzoną. W korze mózgowej niektóre komórki były obkurczone, z ciemnymi jądrami przypominające schorzenie ischemiczne.

Resource type:

Text

Format:

pdf

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open