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File of histopathological evaluation of nervous system diseases (1962) - nr 220/62
Institutional creator:Department of Experimental and Clinical Neuropathology MMRI
Contributor: Place of publishing: Date issued/created: Description:Clinical, anatomical and histological diagnosis
Subject and Keywords:Vascular diseases - encephalomacia
Abstract:Autopsy examination of 55-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin, van Gieson, orcein and Heidenhein method.A vascular focus involving the corpus callosum, bilateral cingulate gyrus and adjacent white matter was present. It was characterized by complete disintegration in the central part and peripheral thinning of the tissue structure. Mesodermal reaction was almost completely absent. In further specimens including basal ganglia at three different levels, no clear focus of malacia was found. Only the leukocyte deposits in a few vessels in the posterior part of the basal ganglia and at the border of the amnion area suggested the presence of very fresh necrosis. Near the foci in the frontal region, the nerve cells were severely damaged, thinned, and ischemically altered. In the basal ganglia, especially in the thalamus, numerous cells were steatotic. The intraparenchymal vessels showed significant fibrosis. Histological diagnosis: Focus encephalomalaciae inveteratis corporis callosi et gyri cinguli lateris utriusąue. Arteriosclerosis.
Resource type: Format: Language: Language of abstract: Rights:Creative Commons Attribution BY 4.0 license
Terms of use:Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -
Digitizing institution:Mossakowski Medical Research Institute PAS
Original in:Library of the Mossakowski Medical Research Institute PAS
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