Title:

File of histopathological evaluation of nervous system diseases (1964) - nr 23/64

Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

Osetowska, Ewa Prof.

Place of publishing:

Warsaw

Date issued/created:

1964

Description:

Clinical, anatomical and histological diagnosis

Subject and Keywords:

Inflammation bacterial- purulent

Abstract:

Histological diagnosis: Meningo-encephalitis septica incipiens. Haemorrhagiae punctatae multiplices. Hyperaemia cerebri generalisata. Autopsy examination of 30-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain frozen sections stained with Hematoxylin-eosin.Meningeal specimens on the convexities and grooves of the cerebellum showed a multiplication of lymphocytic cells, epithelioid cells, and single leukocytes. Accumulations of leukocytes were seen in the vessels at the level of the pons. In the hypothalamic region, in the nucleus supraopticus, below the caput nuclei caudati, astrocytic proliferation and in places microglia were visible. The image was dominated by enormous congestion of the entire vascular network, reaching down to the finest cortical capillaries. In medium and large vessels, hemorrhages and perivascular hemorrhages were seen, often with blood cells mixed with leukocytes in the perivascular spaces. In addition to the obvious signs of vascular barrier disruption, intra-tissue edema was less pronounced. The parenchymal damage was relatively minor: in the basal ganglia, in the thalamus, then in the nucleus supraopticus, in the corpus geniculatum mediale, in the olives and in the nucleus dentatus very numerous steatoses were present.

Resource type:

Text

Format:

pdf

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open