Title:

File of histopathological evaluation of nervous system diseases (1964) - nr 4/64

Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

Śmiałek, Mieczysław dr.

Place of publishing:

Warsaw

Date issued/created:

1964

Description:

Clinical, anatomical and histological diagnosis

Subject and Keywords:

Vascular disease - encephalomacia

Abstract:

Histological diagnosis: Foci Encephalomalacia in regione hemisphaerii cerebelli sinistri atque hemisphaerii dextri cerebri. Thrombosis arteriae cerebri mediae dextrae et encephalomalacia recens suspecta.Autopsy examination of 70-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin and van Gieson method.Several different timed foci of malacia were found in the examined material. In the left cerebellar hemisphere, a well-developed dissection focus with reparative process involving all layers was seen. Within the malacic focus, there were occasional clusters of macrophages with hemosiderin. A layer of Bergmann's glial cells was well preserved. In the parietal region of the right cerebral hemisphere, further foci of malacia in the stage of well-advanced dissection and repair with numerous fibrous elements and macrophage clusters were seen in the white matter and cortex. Leukocytic infiltrates were present locally around the periphery of the foci. The protoplasmic glia was stimulated. Extensive cellular vacuolation was found in the cortex, cells were pale and damaged. Masses of clotted blood morphotic elements: red blood cells, lymphocytes, and leukocytes were seen in the right middle cerebral artery. The arterial wall was atheromatically altered with a thickened elastic membrane, an inner membrane that was stratified over much of the circumference, and a thinning of the muscular layer.

Resource type:

Text

Format:

pdf

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open