Title:

File of histopathological evaluation of nervous system diseases (1965) - nr 71/65

Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

A.Taraszewska, dr

Place of publishing:

Warsaw

Date issued/created:

1965

Description:

Clinical, anatomical and histological diagnosis

Subject and Keywords:

Vascular diseases - encephalomalacia ; Atherosclerosis

Abstract:

Histological diagnosis: Encephalomalacia cum haemorrhagia lobi parietalis sinistri. Arteriosclerosis. Autopsy examination of 66-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with H ematoxylin-eosin and V an Gieson's method.In the left parietal lobe, a foci of malacia in the macrophage clearing phase was found in the white matter, extending to the edge of a fresh hemorrhagic focus. The surrounding tissue contained numerous macrophages and proliferating vessels.Large swelling of white matter, endothelial cells, glial cells, and stimulation of astroglia were observed around this focus. Additionally, loosening of the tissue structure, corresponding to the initial phase of edematous necrosis, was seen in some areas. There were also several smaller foci of necrosis scattered in white matter subcortically with the same morphology as in the main focus, but without hemorrhagic component. In places, clusters of leukocytes, macrophages with hemosiderin, or small cells symptomatic infiltrates were found near the vessels. Atrophy of neurons in the cortex, complete loss of layer structure in some places, ischemic cell disorders and fatty degeneration was found. In the meninges small symptomatic infiltrations were seen. Large vitreous-fibrous changes were noticed in intracerebral vessels.

Resource type:

Text

Format:

pdf

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open