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Wykorzystanie przeciwciał monoklonalnych do celów terapeutycznych
Subtitle:The application of monoclonal antibodies to medical treatment
Creator: Publisher:Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN
Date issued/created: Subject and Keywords: Abstract:In this review contemporary trends in the application of monoclonal antibodies are presented.There is discussed antibody reengineering for humanization of mouse monoclonal antibodies toavoid anti-globulin reaction of patient. Recent modifications of antibody fragments are also outlined. The most common antigenic structures exposed to antibody attack are characterized. Someaspects of human monoclonal antibody production are briefly described. Three most promisingtherapeutic antibodies — bispecific antibodies, immunotoxins, and radiolabeled immunoconjugates — are presented.
Relation:Biotechnologia, vol.21, 2 (1993)-.
Volume: Issue: Start page: End page: Resource type: Detailed Resource Type: Format: Resource Identifier: Source:Biblioteka Instytutu Chemii Bioorganicznej PAN
Language: Language of abstract: Temporal coverage: Rights:Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0
Terms of use: Digitizing institution:Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
Original in:Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
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