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Nucleic acid in sifu hybridization; from ISH to DIRVISH
Subtitle:Nucleic acid in sifu hybridization; from ISH to DIRVISH
Creator: Publisher:Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
Date issued/created: Subject and Keywords: Abstract:In situ hybridization (ISH) provides a highly sensitive method for the detection of specificnucleic acid sequences in cells, nuclei and metaphase chromosomes. This technique has beenimproved continuously since it was first established in 1969. Especially fluorescent in situ hybridization (FISH) rapidly replaced radioactive procedures and became a conventional tool incytogenetic research. ISH plays an increasingly important role in a variety of research areas ofmedicine, genetics and plant breeding. It has been successfully applied for chromosome orchromosome fragments identification, chromosomal abnormalities detection, gene mapping orspecific DNA sequences localization.
Relation:Biotechnologia, vol.29, 2 (1995)-.
Volume: Issue: Start page: End page: Resource type: Detailed Resource Type: Format: Resource Identifier: Source:Library of Institute of Bioorganic Chemistry PAS
Language: Language of abstract: Temporal coverage: Rights:Creative Commons Attribution BY-SA 4.0 license
Terms of use: Digitizing institution:Institute of Bioorganic Chemistry of the Polish Academy of Science
Original in:Institute of Bioorganic Chemistry of the Polish Academy of Science
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