Tytuł:

Interaction of Antisense Oligonucleotides with DNA and Proteins Studied by Fluorescence Polarization Spectroscopy

Inny tytuł:

Interaction of Antisense Oligonucleotides with DNA and Proteins Studied by Fluorescence Polarization Spectroscopy

Twórca:

Murakami, Akira ; Nakaura, Misuzu ; Uematsu, Hiroki ; Fujimura, Naoko ; Iwase, Reiko ; Yamaoka, Tetsuji

Wydawca:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Data wydania/powstania:

1996

Opis:

Polish - Japan Issue

Temat i słowa kluczowe:

biotechnology

Abstrakt:

In order to evaluate the antisense effects in biological systems, the interaction of antisensemolecules with biological substances such as DNAs and human serum proteins was studied byfluorescence depolarization spectroscopy. When an antisense oligonucleotide anchoring fluorescein (F-AS) was mixed with DNAs or proteins, the anisotropy value changed, indicating thatantisense oligonucleotides appreciably interact with DNAs and serum proteins, and that suchinteraction may play important roles on antisense gene regulation.

Czasopismo/Seria/cykl:

Biotechnologia, vol.35, 4 (1996)-.

Tom:

35

Zeszyt:

4

Strona pocz.:

153

Strona końc.:

166

Typ zasobu:

Text

Szczegółowy typ zasobu:

Article

Format:

application/pdf

Identyfikator zasobu:

0860-7796 ; IChB B-31

Źródło:

Library of Institute of Bioorganic Chemistry PAS

Język:

eng

Język streszczenia:

eng

Zakres czasowy:

1988-2010

Prawa:

Creative Commons Attribution BY-SA 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitalizacja:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Lokalizacja oryginału:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open