Tytuł:

Interleukin-2 Gene Therapy Potentiates the Antitumor Effect of Cytostatic Agent in Mice with Advanced Transplantable Tumors

Inny tytuł:

Interleukin-2 Gene Therapy Potentiates the Antitumor Effect of Cytostatic Agent in Mice with Advanced Transplantable Tumors

Twórca:

Glazman-Kuśnierczyk, Halina ; Pajtasz-Piasecka, Elżbieta ; Radzikowski, Czesław

Wydawca:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Data wydania/powstania:

1996

Opis:

Polish - Japan Issue

Temat i słowa kluczowe:

biotechnology

Abstrakt:

terleukin 2 cDNA (X63-mIL-2) were used as the slow-release system of IL-2 for immunotherapyand chemoimmunotherapy in mice challenged with subcutaneous injections of different non-related tumors (MCA induced fibrosarcomas BFSl and F-69-3, colon carcinoma C38). The combination of one dose of the cytostatic agent (bromoanalog of ifosfamide) administration withsubsequent peritumoral injections of the cytokine-producing cells was observed to be more efficient in the tumor growth inhibition as compared with the cytostatic alone.

Czasopismo/Seria/cykl:

Biotechnologia, vol.35, 4 (1996)-.

Tom:

35

Zeszyt:

4

Strona pocz.:

68

Strona końc.:

79

Typ zasobu:

Text

Szczegółowy typ zasobu:

Article

Format:

application/pdf

Identyfikator zasobu:

0860-7796 ; IChB B-31

Źródło:

Library of Institute of Bioorganic Chemistry PAS

Język:

pol

Język streszczenia:

eng

Zakres czasowy:

1988-2010

Prawa:

Creative Commons Attribution BY-SA 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitalizacja:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Lokalizacja oryginału:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open