Title:

Interleukin-2 Gene Therapy Potentiates the Antitumor Effect of Cytostatic Agent in Mice with Advanced Transplantable Tumors

Subtitle:

Interleukin-2 Gene Therapy Potentiates the Antitumor Effect of Cytostatic Agent in Mice with Advanced Transplantable Tumors

Creator:

Glazman-Kuśnierczyk, Halina ; Pajtasz-Piasecka, Elżbieta ; Radzikowski, Czesław

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Date issued/created:

1996

Description:

Polish - Japan Issue

Subject and Keywords:

biotechnology

Abstract:

terleukin 2 cDNA (X63-mIL-2) were used as the slow-release system of IL-2 for immunotherapyand chemoimmunotherapy in mice challenged with subcutaneous injections of different non-related tumors (MCA induced fibrosarcomas BFSl and F-69-3, colon carcinoma C38). The combination of one dose of the cytostatic agent (bromoanalog of ifosfamide) administration withsubsequent peritumoral injections of the cytokine-producing cells was observed to be more efficient in the tumor growth inhibition as compared with the cytostatic alone.

Relation:

Biotechnologia, vol.35, 4 (1996)-.

Volume:

35

Issue:

4

Start page:

68

End page:

79

Resource type:

Text

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796 ; IChB B-31

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open