Title:

Files for neuromuscular diseases (2011) - nr 8/11-2

Creator:

Fidziańska-Dolot, Anna (1930–2015)

Contributor:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular

Place of publishing:

Warsaw

Date issued/created:

2011

Description:

Muscle segment examination in light & electon microscopy

Subject and Keywords:

Myopathy

Abstract:

A quadriceps sinister biopsy from 3-year-old patinet with suspected myopathy was taken and examined. Electronmicroscopy analysis revealed a few fibers of normal diameter and numerous myotube-like fibers. Myotube-like fibers were much smaller than normal and possessed centrally located, large, singular, composed mainly of eurochromatin nuclei. No significant deficiencies in the myofibrils structure were observed. In some of the fibers significantly damaged, swollen mitochondria, characterized by a loss of mitochondrial cristae were seen. The fibers of the intramuscular nerve show the presence of multiaxonal fibers. Fibers characterized by myelin splitting and incomplete myelination were observed. Conclusions: microscopic image may indicate a defect in the maturation process of the muscular system.

Resource type:

Text ; Image

Detailed Resource Type:

Photography ; Files

Format:

pdf

Language:

pol

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open