Title:

Distribution of transcription factor binding sites along 5’-upstream sequences of genes: estimation of minimal promoters and upstream regulatory regions

Subtitle:

Distribution of transcription factor binding sites along 5’-upstream sequences of genes: estimation of minimal promoters and upstream regulatory regions

Creator:

Malewski, Tadeusz ; Glazko, Galina ; Sazanov, Alexei

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Date issued/created:

2004

Subject and Keywords:

biotechnology

Abstract:

Precise analysis of gene transcription regulation requires accurate estimation of gene regulatory elements. Transcription factors (TF) binding sites are distributed unevenly along gene 5'-upstream sequences. The analysis of gene 5'-upstream sequences showed the presence of high-density regions of transcription factor binding sites (HDR). The first FIDR adjacent to the transcription start point corresponds to a minimal promoter, and the 5’-end of l-HDR corresponds to the 5’-end of minimal promoter.

Relation:

Biotechnologia, vol.66, 3 (2004)-.

Volume:

66

Issue:

3

Start page:

225

End page:

237

Resource type:

Text

Detailed Resource Type:

Article

Format:

application/pdf ; application/pdf

Resource Identifier:

0860-7796

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open