Object structure
Title:

Mechanisms determining bacterial biofilm resistance to antimicrobial factors

Subtitle:

Mechanisms determining bacterial biofilm resistance to antimicrobial factors

Creator:

Czaczyk, Katarzyna ; Myszka, Kamila

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Date issued/created:

2007

Subject and Keywords:

biotechnology

Abstract:

Bacterial biofilm resistance is a very serious problem of modern medicine and industry practice. Microorganisms forming biofilm initiate multilevel resistance mechanisms that protect cells against antibacterial substances. This resistance is higher than antibiotics and disinfectants tolerance of planktonic bacteria. Ineffective of antibacterial compounds action on biofilm depends on biofilm structure, slowing down the antibiotics diffusion speed, environmental factors in which biofilm is formed, the presence of capsule of bacteria and the activity of “efflux pumps” proteins. The process of signal molecules formation by bacteria and releasing them to the medium is also very relevant aspect. In this paper, the changes in the molecular level that induces bacterial biofilm resistance against antimicrobial agents are also described.

Relation:

Biotechnologia, vol.76, 1 (2007)-.

Volume:

76

Issue:

1

Start page:

40

End page:

52

Resource type:

Text

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796 ; IChB B-72

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

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