Title:

Files for neuromuscular diseases (2010) - nr 32/10

Creator:

Fidziańska-Dolot, Anna (1930–2015)

Contributor:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular

Place of publishing:

Warsaw

Date issued/created:

2010

Description:

Muscle segment examination in light & electron microscopy

Subject and Keywords:

Metabolic myopathy

Abstract:

A 41-year-old patient with suspected metabolic miopathy was examined. A biopsy of quadricepssinister was performed.Majority of muscle fibers showed normal diameter and architecture, unchanged, laying undersarcolemma nuclei were seen.Electron microscopy revealed numerous fat droplets within the muscle fibers.Abnormal mitochondria with crystalline inclusions were observed.A defect of mitochondrial enzymes was suspected. Biochemical evaluation of carnitinepalmitoyltransferase in the muscle tissue was performed and the result was 1,5 nM/mgB/min. (Norm6,5-18 nM/mgB/min.).Microscopic image of the biopsy and reduced carnitine palmitoyltransferase suggest metabolicmyopathy CPT deficiency type.

Resource type:

Text ; Image

Detailed Resource Type:

Photography ; Files

Format:

pdf

Language:

pol

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open