Title:

Biochemical signs of early rejection of liver allografts in dogs

Creator:

Olszewski, Waldemar ; Polański, Jerzy ; Sawicki, Zbigniew ; i in.

Publisher:

Polska Akademia Nauk

Place of publishing:

Warszawa

Date issued/created:

1973

Type of object:

Journal/Article

Abstract:

Biochemical alterations during early rejection of allogeneic liver transplants were studied in 17 dogs. The animals were divided into 3 groups: 1) orthotopic liver transplantation with immunosuppressive therapy, 2) orthotopic liver transplantation without immunosuppressive therapy, 3) immunosuppressive therapy as in group 1, but no transplantation. Results of biochemical studies indicate that the most typical sign of early rejection of the liver is an increase in serum biblirubin level. High serum bilirubin points to advanced and usually irreversible alterations in the liver parenchyma. Efforts to mitigate the rejection proces with immunosuppressive drugs thus far are usually ineffective.

Relation:

Acta Medica Polona

Volume:

14

Issue:

2

Start page:

161

End page:

166

Resource type:

Text

Detailed Resource Type:

Article

Format:

pdf

Language:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Copyright holder:

Olszewski, Waldemar

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open