Tytuł:

Prolongation of rabbit -to-dog liver xenograft survival in recpients pretreated with rabbit blood

Twórca:

Olszewski, Waldemar ; Łukasiewicz, Hanna

Wydawca:

Polska Akademia Nauk

Miejsce wydania:

Warszawa

Data wydania/powstania:

1973

Typ obiektu:

Journal/Article

Abstrakt:

An attempt was made to prolong rabbit-to-dog liver graft survival by pretreatment of recipients with donor species blood elements. Recipients were given intraarterially whole blood, washed erythrocytes, erythrocyte stroma, leukocytes, and rabbit plasma 1 hr befor transplantation of rabbit liver. Pretreatment with whole blood or red cells was followed by acute depletion of hemagglutinins, hemolysins, complement, and decrease in platelet and leukocyte counts. Rabbit livers transplanted at that time had a 10—20-fold longer survival time. Pretreatment with donor leukocytes only slightly prolonged graft survival, whereas rabbit plasma had no effect at all. It may be concluded that recipient circulating antibodies agglutinating donor erythrocytes are responsible for triggering the process of hyperacute rejection.

Czasopismo/Seria/cykl:

Acta Medica Polona

Tom:

14

Zeszyt:

2

Strona pocz.:

131

Strona końc.:

138

Typ zasobu:

Text

Szczegółowy typ zasobu:

Article

Format:

pdf

Język:

eng

Prawa:

Creative Commons Attribution BY 4.0 license

Zasady wykorzystania:

- ; Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at:

Właściciel praw autorskich:

Olszewski, Waldemar

Digitalizacja:

Mossakowski Medical Research Institute PAS

Lokalizacja oryginału:

Library of the Mossakowski Medical Research Institute PAS

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open