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Properties of brain mitochondria in conditions of ischemia and nembutal anaesthesia in guinea-pigs
Creator:Majewska, Danuta ; Gromek, Andrzej ; Strosznajder, Joanna
Publisher: Place of publishing: Date issued/created: Type of object: Abstract:The investigations concerned mitochondrial ability of oxidative phosphorelation activity and mitochondrial ATPases, free acids (FFA content and the proceses of swelling of the mitochondria. Barbiturate anasthesia was shown to attenuate the distrubance of mitochondrial metabolic function due to anoxia, The in vitro studies demonstrate that the action of acetylocholine is similar to that of narcosis. Acetylocholine added to the medium docreases the amount of released fatty acids and improves RCI coefficient values. It is suggested that acetylocholine may be one of the factors rsponsible for the observed "protective" effect of barbiturate anaesthesia.
Relation:Bulletin de l'Academie Polonaise des Sciences. Serie des Sciences Biologiques
Volume: Issue: Start page: End page: Resource type: Detailed Resource Type: Format: Language: Language of abstract: Rights:Licencja Creative Commons Uznanie autorstwa 4.0
Terms of use:Zasób chroniony prawem autorskim. [CC BY 4.0 Międzynarodowe] Korzystanie dozwolone zgodnie z licencją Creative Commons Uznanie autorstwa 4.0, której pełne postanowienia dostępne są pod adresem: ; -
Copyright holder: Digitizing institution:Instytut Medycyny Doświadczalnej i Klinicznej im. M. Mossakowskiego Polskiej Akademii Nauk
Original in:Biblioteka Instytutu Medycyny Doświadczalnej i Klinicznej im. M. Mossakowskiego PAN
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