Title:

Properties of brain mitochondria in conditions of ishemia and nembutal anesthesia in guinea-pigs

Creator:

Majewska, Maria Dorota ; Gromek, Andrzej ; Strosznajder, Joanna

Publisher:

PWN

Place of publishing:

Warszawa

Date issued/created:

1974

Type of object:

Journal/Article

Abstract:

The investigations concerned mitochondrial ability of oxidative phosphorelation activity and mitochondrial ATPases, free acids (FFA content and the proceses of swelling of the mitochondria. Barbiturate anasthesia was shown to attenuate the distrubance of mitochondrial metabolic function due to anoxia, The in vitro studies demonstrate that the action of acetylocholine is similar to that of narcosis. Acetylocholine added to the medium docreases the amount of released fatty acids and improves RCI coefficient values. It is suggested that acetylocholine may be one of the factors rsponsible for the observed "protective" effect of barbiturate anaesthesia.

Relation:

Bulletin de l'Academie Polonaise des Sciences. Serie des Sciences Biologiques

Volume:

22

Issue:

4

Start page:

267

End page:

273

Resource type:

Text

Detailed Resource Type:

Article

Format:

application/pdf

Language:

eng

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Copyright holder:

Strosznajder, Joanna

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open