@misc{Mossakowski_Mirosław_Jan_(1929–2001)_Effect_1987, author={Mossakowski, Mirosław Jan (1929–2001) and Gadamski, Roman (1933–2015)}, volume={25}, number={4}, copyright={Creative Commons Attribution BY 4.0 license}, address={Wrocław ; Warszawa ; Kraków}, journal={Neuropatologia Polska}, howpublished={online}, year={1987}, publisher={Zakład im. Ossolińskich - Wydawnictwo Polskiej Akademii Nauk}, language={pol}, abstract={The protective effect of Nimotop (Bayer) — a calcium channel blocker, beingan equivalent of nimodipine, on the development of selective damage of CAi neuronsof Ammon’s horn resulting from short-term ischemia of forebrain in Mongoliangerbils was evaluated. The experimental animals, subjected to 7.5 min bilateralligation of common carotid arteries were given the drug in a dosis of 1 mg/kgbody weight in the form of intraperitoneal injection at various periods in relationto cerebral ischemia. In group 1 — Nimotop was administered twice — 60 mjnbefore ischemia and 5 h after arterial release. In group 2 a double dosis of thedrug was given 15 min prior to carotid occlusion and in 3rd hour of the recirculation.In group 3 the scheme applied in group 2 was supplemented with a thirddosis of Nimotop given 24 h following cerebral ischemia. The latter was the timeof a single drug dosis application in group 4. The control animals were subjectedto cerebral ischemia with no medication.}, type={Text}, title={Effect of a calcium channel blocker on the development of ischemic neuron damage in sector CA1 of the horn of Ammon in Mongolian gerbils}, URL={http://rcin.org.pl./Content/68727/PDF/1987_25_4_439-450.pdf}, keywords={Calcium, Ischemic neuron damage, CA1, Ammon's horn}, }